myeloma {collett}R Documentation

Survival of multiple myeloma patients

Description

Patients diagnosed with multiple myeloma who were diagnosed and treated with alkylating agents at West Virginia University Medical Center for ages 50-80 years.

Usage

myeloma

Format

A data frame with 48 rows and 10 variables:

patient

integer for a patient identifier

time

integer survival time in months

status

integer for status at follow-up (0=Alive, 1=Dead)

age

integer age at diagnosis in years

sex

integer for sex of the patient (1=male, 2=female)

bun

integer level of blood urea nitrogen at diagnosis (unit assumed to be mg/dL based on the normal range for adults reported by https://en.wikipedia.org/wiki/Blood_urea_nitrogen)

ca

integer serum calcium at diagnosis in mg/dL

hb

double for serum hemoglobin level at diagnosis in g/dL (equivalently, grams per 100 mL)

pcells

integer percent of plasma cells in the bone marrow at diagnosis

protein

integer indicator for whether or not the Bence-Jones protein was present in the urine at diagnosis (0=absent, 1=present)

Details

Krall et al (1975) did not provide the units for all of these measurements. In their analyses, they used some data transformations: log(bun). Collett (2023) converted data from Krall et al (1975): BUN is reported by Krall and colleagues as X1=log(BUN), however the log base and unit is unclear; Krall and colleagues reported for 65 individuals, including those younger than 50 and older than 80.

References

Krall JM, Uthoff VA, Harley JB. A step-up procedure for selecting variables associated with survival. Biometrics. 1975 Mar 1:49-57. doi:10.2307/2529709

Examples

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[Package collett version 0.1.0 Index]