extr_tox {extractox} | R Documentation |
Extract Toxicological Information from Multiple Databases
Description
This wrapper function retrieves toxicological information for specified chemicals by calling several external functions to query multiple databases, including PubChem, the Integrated Chemical Environment (ICE), CompTox Chemicals Dashboard, and the Integrated Risk Information System (IRIS) and other.
Usage
extr_tox(casrn, verbose = TRUE, force = TRUE, delay = 2)
Arguments
casrn |
A character vector of CAS Registry Numbers (CASRN) representing the chemicals of interest. |
verbose |
A logical value indicating whether to print detailed messages. Default is TRUE. |
force |
Logical indicating whether to force a fresh download of the EPA PPRTV database. Default is TRUE. |
delay |
Numeric value indicating the delay in seconds between requests to avoid overwhelming the server. Default is 3 seconds. |
Details
Specifically, this function:
Calls
extr_monograph
to return monographs informations from WHO IARC.Calls
extr_pubchem_ghs
to retrieve GHS classification data from PubChem.Calls
extr_ice
to gather assay data from the ICE database.Calls
extr_iris
to retrieve risk assessment information from the IRIS database.Calls
extr_comptox
to retrieve data from the CompTox Chemicals Dashboard.
Value
A list of data frames containing toxicological information retrieved from each database:
- who_iarc_monographs
Lists if any, the WHO IARC monographs related to that chemical.
- pprtv
Risk assessment data from the EPA PPRTV
- ghs_dat
Toxicity data from PubChem's Globally Harmonized System (GHS) classification.
- ice_dat
Assay data from the Integrated Chemical Environment (ICE) database.
- iris
Risk assessment data from the IRIS database.
- comptox_list
List of dataframe with toxicity information from the CompTox Chemicals Dashboard.
Examples
condathis::with_sandbox_dir({ # this is to write on tempdir as for CRAN policies # nolint
Sys.sleep(4) # To avoid overwhelming the server
extr_tox(casrn = c("100-00-5", "107-02-8"), delay = 4)
})