LTFGRS-package {LTFGRS}R Documentation

LTFGRS: Implementation of Several Phenotype-Based Family Genetic Risk Scores

Description

Implementation of several phenotype-based family genetic risk scores with unified input data and data preparation functions to help facilitate the required data preparation and management. The implemented family genetic risk scores are the extended liability threshold model conditional on family history (LT-FH++) from Pedersen (2022) doi:10.1016/j.ajhg.2022.01.009 and Pedersen (2023) https://www.nature.com/articles/s41467-023-41210-z, Pearson-Aitken Family Genetic Risk Scores (PA-FGRS) from Krebs (2024) doi:10.1016/j.ajhg.2024.09.009, and family genetic risk score by Kendler (2021) doi:10.1001/jamapsychiatry.2021.0336.

Author(s)

Maintainer: Emil Michael Pedersen emp@ph.au.dk

Authors:

Other contributors:

See Also

Useful links:


[Package LTFGRS version 1.0.0 Index]