chem.invivo.PK.aggregate.data {httk} | R Documentation |
Parameter Estimates from Wambaugh et al. (2018)
Description
This table includes 1 and 2 compartment fits of plasma concentration vs time data aggregated from chem.invivo.PK.data, performed in Wambaugh et al. 2018. Data includes volume of distribution (Vdist, L/kg), elimination rate (kelim, 1/h), gut absorption rate (kgutabs, 1/h), fraction absorbed (Fabsgut), and steady state concentration (Css, mg/L).
Usage
chem.invivo.PK.aggregate.data
Format
data.frame
Author(s)
John Wambaugh
Source
Wambaugh et al. 2018
References
Wambaugh JF, Hughes MF, Ring CL, MacMillan DK, Ford J, Fennell TR, Black SR, Snyder RW, Sipes NS, Wetmore BA, others (2018). “Evaluating in vitro-in vivo extrapolation of toxicokinetics.” Toxicological Sciences, 163(1), 152–169. doi:10.1093/toxsci/kfy020.
[Package httk version 2.6.1 Index]