lr_db {PopComm} | R Documentation |
Ligand-Receptor Pair Database
Description
A comprehensive database of human ligand-receptor pairs with gene/protein identifiers
and supporting evidence from literature. Data imported from human_lr_pair.txt
.
Usage
lr_db
Format
A data frame with 3,398 rows (pairs) and 10 columns:
- lr_pair
Character. Unique identifier for ligand-receptor pair, formatted as "LIGAND_RECEPTOR" (e.g., "SEMA3F_PLXNA3")
- ligand_gene_symbol
Character. Official HGNC symbol of the ligand gene (e.g., "SEMA3F")
- receptor_gene_symbol
Character. Official HGNC symbol of the receptor gene (e.g., "PLXNA3")
- ligand_gene_id
Integer. Entrez Gene ID of the ligand gene (NCBI identifier)
- receptor_gene_id
Integer. Entrez Gene ID of the receptor gene (NCBI identifier)
- ligand_ensembl_protein_id
Character. Ensembl protein ID of the ligand (e.g., "ENSP00000002829")
- receptor_ensembl_protein_id
Character. Ensembl protein ID of the receptor (e.g., "ENSP00000358696")
- ligand_ensembl_gene_id
Character. Ensembl gene ID of the ligand (e.g., "ENSG00000001617")
- receptor_ensembl_gene_id
Character. Ensembl gene ID of the receptor (e.g., "ENSG00000130827")
- evidence
Character. PubMed IDs (PMIDs) supporting the interaction, comma-separated (e.g., "15721238")
Source
Source from CellTalkDB (PMID: 33147626).