SIS_combo {SMAHP} | R Documentation |
SIS combo
Description
A function for SIS + SIS combo.
Usage
SIS_combo(X, M, C, time, status, p_adjust_option = "BH", thres = 0.05)
Arguments
X |
An n by p matrix of exposures. |
M |
An n by p matrix of mediators. |
C |
An n by p matrix of covariates. |
time |
A vector of survival time of samples. |
status |
A vector of status indicator: 0=alive, 1=dead. |
p_adjust_option |
The method for multiple correction. Option include q-value, holm, hochberg, hommel, bonferroni, BH, BY, and fdr. Default is BH. |
thres |
Threshold for determining significance. |
Value
A list which includes the final p-value matrix (p_final_matrix), adjusted p-value matrix (p_adjusted_matrix) and mediation-exposure matrix (p_med_matrix).
Examples
data(example_dat)
surv_dat <- example_dat$surv_dat
SIS_combo(example_dat$X, example_dat$M, example_dat$C, time = surv_dat$time,
status = surv_dat$status)
[Package SMAHP version 0.0.5 Index]