extract_tto {vigicaen} | R Documentation |
Time to onset extraction
Description
extract_tto()
collects
all available time to onsets for a set of drug-adr pairs.
Usage
extract_tto(.data, adr_s, drug_s, tto_time_range = 1)
Arguments
.data |
A |
adr_s |
A character string. The name of the adr column. (see details) |
drug_s |
A character string. The name of the drug column. (see details) |
tto_time_range |
Incertitude range of Time to onset, in days. Defaults to 1 as recommended by umc |
Details
Extraction of (maximum available) time between drug initiation
and event onset. This runs at the drug-adr pair level.
You will need a link
data.table, see link_
, on which
you have added drugs and adrs with add_drug()
and add_adr()
.
Uppsala Monitoring Centre recommends to use only cases where the incertitude
on time to onset is less than 1 day. You can change this with tto_time_range
.
You might want to use desc_tto()
to obtain summary statistics of
time to onset, but extract_tto()
is useful to get the raw data and plot it,
for instance with ggplot2
.
Value
A data.frame with
All available time to onsets for this combination (column
tto_max
).-
adr_s
anddrug_s
, same as input. -
UMCReportId
, the unique identifier of the case.
See Also
link_
, desc_tto()
, add_drug()
, add_adr()
, desc_dch()
, desc_rch()
Examples
link_ <-
link_ |>
add_drug(
d_code = ex_$d_groups_drecno,
drug_data = drug_
) |>
add_adr(
a_code = ex_$a_llt,
adr_data = adr_
)
extract_tto(.data = link_,
adr_s = "a_colitis",
drug_s = "pd1")
extract_tto(.data = link_,
adr_s = c("a_colitis", "a_pneumonitis"),
drug_s = c("pd1", "ctla4"))